MicroStudio Won't Open

[silverea]

I and the Technician did that several times, we also installed the program on a computer at his shop and it worked great, read all the drives...no problems. It just won't work on mine anymore and he can't find any other problems with my computer. Other programs I've had for years still see my Plextor drives as before. One more note, right after the program is reinstalled, it will open as normal 1 or 2 times (doesn't see the drives however) and then it takes about 5 minutes or so to open after that, still not seeing the drives. I tried doing the uninstall, restart and reinstall just before I responded to this message, but to no avail.