Randy, for one thing Microstudio does not support a secondary display. Yes you can move it over on to an extended desktop, but this is no longer supported for you to do this. Microstudio is supposed to be for working with your music/karaoke files and not for a show situation.
That said resolution especially different resolutions can cause sync problems, but not sure re-testing the drive and refreshing again in any specific resolution would make a difference. Resolution isn't a big problem for either Hoster or Microstudio except that they should be the same.
Looking at your specs, if it is correct tells me your screen repaint is being caused by a secondary graphics card with way to little memory. 4 MB??
By the way the error message you sent was going to Microsoft and not MTU. That is like sending it to the trash as they don't pay any attention to those.
