Billy,
I know you don't do this for a living... and have turned down other venues, or have recommended other KJ's to fill gigs that you didn't need or want!
Why drive 45 minutes, when another gig may open up closer to you, once word of mouth gets around that you are available?
Different set of rules if you were in a small underpopulated area, that had only a small selection of probable candidates for Karaoke gigging, that a lot of us have to endure, because of economy and location...
I travel 10 - 20 miles to most of my gigs (5) right now, and have not turned down farther private party gigs, but I'm usually compensated for my time and mileage, for these private parties!
Weigh the benefits against the difficulty, and you will be able to answer your own question!
Best of luck in finding a closer venue in the near future!