The short answer is no. You might try the with a windows virtual machine or WINE, but I doubt it will work. The newer intel macs should work OK with a separate partition of windows, but I am sure there will be some hurdles to jump over.
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Test machine:
Vista Home Premium / Toshiba Satelitte X205 / 2.0GHz Core2 Duo / 2GB memory / 2x NVIDIA GeForce 8600M GT
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