I prefer a desktop only because it's more readily upgradable. I use a M-Audio pro audio sound card with balanced 1/4" connetors (although have a great USB audio interface for my laptop now that also uses 1/4" balanced jacks as well), video cards can be swapped out easily, memory, etc. Laptops are a little more inconvenient in upgrading and servicing on site - aside from just simply having a complete 2nd laptop for backup, a HECK of a lot more convenient as far as setup though!
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Show PC Lenovo nVidia 3.2ghz proc
Win 8.1 64bit
Vid: nVidia GT720 2gb mem
Aud: Lexicon Alpha
Mem: 8gb ram
HD: 1tb int/1tb int
Test PC ASUS AMD 4ghz 8 core proc
Win 7 Pro 32 bit
Vid: LP Radeon HD 5450 Video Card - 1GB
Aud: Lexicon Omega USB I/O Interface
Mem: 16gb ram
HD: 1TB/1TB
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