It's not so important what is installed on your computer. What is more important is what is running in the background. Un-installing things like paint is still a good idea. It will save you hard drive space which can make a difference in the overall performance of the Window's swap file. It can also make a cleaner defrag. The biggie is services and unnecessary "helper" programs. These are the things to look out for.
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Test machine:
Vista Home Premium / Toshiba Satelitte X205 / 2.0GHz Core2 Duo / 2GB memory / 2x NVIDIA GeForce 8600M GT
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