[ddouglass]

The database only stores the location of the KMA files, Artist name, Title and some other information, but not the files themselves. If you edit a song (change something in the title or a characteristic when you hit apply this information is saved to the database and to the KMA file header. With the error message you got it is saying that Hoster cannot find the file to save the new information to. This indicates a problem with the drive not with the database.
Run Chkdsk on the drive to check for problems. If there are a lot of Bad Sectors it is time to replace the drive....quickly. You should have a back-up of all your KMA files to keep this from being a major problem.